Exact(1)
Biological therapies including IFN-α have shown a real, but minimal, effect in malignant melanomas (Pavlick et al, 2003) and the effects of IL-2, as a treatment for malignant melanoma, are not yet clearly defined.
Similar(59)
In our study, the P25-transgene had massive effects on the transcriptomes of the leaves, but minimal effects in the flowers, although the gene was expressed on equal level in both organs.
A robust DE effect was apparent in WKY (377 genes with 5% FDR correction and significance at p < 0.01) but minimal effect was evident in SH rats.
Indeed, in isolated mitochondria, addition of IGF-I significantly increased Thr-389 phosphorylation of p70S6K in the βIRKOs but had minimal effect in the controls (Fig. 3C).
As shown the representative recordings in Figure 6A1 and I V curves in Figure 6A2, 10 µM Gd3+ suppressed the ILeak in the control groups, but with minimal effect in U-type dsRNA/siRNA treated groups.
In sorghum, Ma1 (SbPRR37) increases photoperiod sensitivity by repressing expression of SbEHD1 and SbCN8/12, resulting in delayed flowering in LD but with minimal effect in SD [ 1].
In addition, OSU-03012 led to cell viability decline and induced apoptosis in RMS cells (RH30 and SMS-CTR) but had minimal effect in normal human cells.
We found that partially or completely inhibiting ERK and/or MEK increased AP1 homodimers in environments featuring high values of TGF-α stimulation, but had minimal effect in those with low values of TGF-α stimulation.
As shown the representative recordings in Figure 7A1 and I V curves in Figure 7A2, 0.5 mM [Ca]o depolarized the membrane potential in the control groups, but with a minimal effect in U-type dsRNA/siRNA treated groups.
Results The high sensitivity troponin I assay noticeably increased the diagnosis of myocardial infarction in women (from 11% to 22%; P<0.001) but had a minimal effect in men (from 19% to 21%, P=0.002).
Behind the scenes, senior administration officials acknowledged that such moves would have minimal effect in stopping the overall flow of Central Americans.
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