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EPI shows a pronounced distinction between bone and adjacent musculature, but low spatial resolution limits the use of this technique [17].
One array is developed for a large area tactile sensor that has good sensitivity but low spatial resolution, similar to human body skin.
By recording a live-cell movie of the vesicles at high temporal (but low spatial) resolution, her team can track vesicle motion, overlaying those trajectories on a STORM image of microtubule positions.
Whilst it is difficult to extrapolate these functional studies (particularly for EEG given its high temporal but low spatial resolution) to our DTI results demonstrating white matter changes in specific regions, these data at least indicate that sex steroids such as testosterone can impact on brain function.
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The USI is feasible for clinical studies, but its low spatial resolution (~30 μm) and lack of functional information limit its applications for microvascular imaging.
MRI offers the highest diagnostic sensitivity for the detection of small cancers and has the advantage of avoiding ionizing radiation, but has low spatial resolution, is cost-intensive and requires the use of intravenous contrast agents [ 7].
2) Seeing is believing, but given the low spatial resolution of the methods certain structural assumptions need to be made with regard to fiber dimensions and as such compaction calculations are perhaps potentially in error?
For PET, several radiopharmaceuticals are already in clinical use with high sensitivity and specificity but with relatively low spatial resolution, although some studies have found the technique sufficient for inflammation localization.
Diffusion-weighted MRI has a great potential to provide early response indicator based on the altered cell membrane and cell death, but the relatively low spatial resolution and image distortion limit DWI to become a good tool for evaluating the extent of residual disease after NAC.
10.7554/eLife.08646.024 Author response image 1. DOI: http://dx.doi.org/10.7554/eLife.08646.024 2) Seeing is believing, but given the low spatial resolution of the methods certain structural assumptions need to be made with regard to fiber dimensions and as such compaction calculations are perhaps potentially in error?
Alternatively, current morphological models, algorithms that correlate urban geometries with aerodynamic properties, are inexpensive but can only provide results with low spatial resolution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com