However, 2D similar compounds can make highly experienced medicinal chemists suggest similar targets but it have less probability to give novel pharmacological effects in comparison to 3D similarity compounds [16, 17].
Changing the two non-negative shape parameters, alpha and beta, to that of a more realistic but less conservative probability density function (e.g., alpha = 2 and beta = 5) did not affect the outcome.
But the commission has argued that the benefits — particularly a healthier banking industry with less probability of government bailouts — would outweigh the short-term costs.
"The straighter the path, the less probability of damaging the paper," he explained.
The portraits have been ascribed to C. Dusart, and, with less probability, to L. Gaultier.
Likewise, genes showing high FC difference between the two cell types but having minimal RNA expression in either cell type (that is, normalized read counts<300, indicating the less probability of robust protein expression) would also be eliminated.
Patents from Japan have less probability of being opposed and are less likely to be revoked than the other countries.
"If these paleoclimatic constraints apply to the future, as predicted by our model, the results imply less probability of extreme climatic change than previously thought," Schmittner stated in a press release.
There is less probability of an election night surprise when the polls are fairly consistent with one another, as they are in this case.
In relation to socio-demographic variables, Antisocial Personality Disorder patients have less probability of being working or studying (9.1% vs. 47.9%).
