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In naive human immunodeficient virus (HIV -infected patients, emtricitabine was more efficacious tHIV -infected but less efficacious than lamivudine; in expatientsd patiemtricitabineine and stavudine had equal efficacy.
Its widespread use was highly successful in reducing malaria mortality but less efficacious in reducing the number of cases.
Commercially available ocular drug delivery systems are effective but less efficacious to manage diseases/disorders of the anterior segment of the eye.
Vaccine efficacy of AdPvs25 was slightly higher than to a recombinant Pvs25 protein mixed with aluminum hydroxide, but less efficacious than the protein emulsified with incomplete Freund's adjuvant.
Oxotremorine and pilocarpine were more potent (EC50= 1.0 and 1.2 µM respectively) but less efficacious (Emax= 2.8 and 1.6-fold increase respectively).
Increase in terminal hair count was comparable to the short-term trials of 5%% minoxidil topical solution and 1 mg/day finasteride, but less efficacious than longer term (≥1 year) trials.
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We conclude that (1) dexrazoxane does not interfere with the antileukemic effect of doxorubicin, (2) intensive intrathecal chemotherapy is as effective as cranial radiation in preventing CNS relapse in standard-risk patients, and (3) once-weekly Erwinia is less toxic than E coli asparaginase, but also less efficacious.
Some results of such an exploration are shown in Table 2. Table 2 shows that increasing VMAT2 could elevate concentrations of extracellular dopamine and total dopamine, but is less efficacious than MAO inhibition.
Synthetic pyrethroids are highly efficacious against PAAM and adult females [ 14] but reportedly less efficacious against chalimus stages [ 15, 16].
This strategy is often effective in patients with less severe lung diseases, but is less efficacious in patients with ARDS with high shunt fractions [ 6].
Neodymium YAG laser vitreolysis has been used to treat vitreous floaters [ 2, 3], but is less efficacious than vitrectomy which completely resolves symptoms in 93% of eyes [ 4].
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