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The TLR11 gene exists in humans but is not functional due to the presence of a stop codon in the leucine rich repeats [52].
Since the central clock in Per1−/− Per2m/m mice is driven by environmental light in LD cycles but is not functional in DD cycles [52], these mice could maintain a circadian rhythm of urinary catecholamine levels in LD cycles but not in DD cycles.
We show here that CFTR is present in both cell types, but is not functional in trp4 deficient endothelial cells.
This strategy is adequate in a task with a very limited set of stimuli and no demands on semantic interpretation, but is not functional in a naturalistic comprehension task.
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It was a real place, but was not functional - which I'm glad because it's really hard to shoot in a real prison.
Similar results were obtained with SUMO2 and the QFI mutant, suggesting that both SUMO mutants can be conjugated to CtBP, but are not functional for Pc2 E3 activity (Figure 7C).
The ICC was set up but was not functional (no regular meetings, no infection control activities realised).
In PepTSt, the Glu400Ala mutation failed to express; similar mutations in human PepT1 and YjdL express but were not functional (Bolger et al, 1998; Jensen et al, 2011).
However, expression profiling may yield many genes that respond indirectly, whereas ChIP may yield many non-functional binding sites, i.e., binding sites that were detected by ChIP, but were not functional for transcriptional regulation.
This was not possible, however, due to the degeneracy of the splicing machinery and because certain sequences may act as donor splice sites in some sequences but are not functional in others.
It's there as a premises but it is not functional".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com