Results: After incubation in medium from hypoxic cytotrophoblasts, arterial segments were more responsive to phenylephrine and to potassium-induced constriction but were less responsive to methacholine, and the vasomotor activity was increased compared with that found in vessels incubated in control medium.
Larvae were attracted to a blend of these compounds, but were less responsive to this mixture than to a presentation of each molecule alone, which suggests an interaction between the two pheromones.
In general, the EQ-5D Index and VAS showed good reliability and responsiveness in comparison to other generic measures such as the SF-12 but were less responsive than disease-specific measures such as the KCCQ [ 26, 27].
In particular, the FACT-P was responsive in both phase 3 registration studies for abiraterone as well as phase 3 studies for enzalutamide and docetaxel for patients with mCRPC but was less responsive in the registration study for radium Ra 223 dichloride described in the SmPC [[ 7],[ 28],[ 29],[ 34]].
However, recent data from our laboratory, utilising an improved culture method for primary MM cells, have demonstrated that in the hyperdiploid group, cyclin D2-expressing tumours are more sensitive to growth factors than cyclin D1-expressing tumours, but are less responsive when compared with cyclin D2-expressing cases harbouring t(14 16) or t(4 14).
In addition PI is less responsive than AAQM in response to buffer emptiness.
"It's analogous to a primary cancer that's very drug-responsive but once it transforms itself and metastasizes is less responsive," Bob Post explains.
And though the Supreme Court is less responsive to shifts in popular opinion than state lawmakers, Congress or the president, it is not immune to them.
This is due to the fact that PI is less responsive and this results in periods of buffer emptiness.
