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Deletion of CPR3 did not affect the release of EndoG but instead caused a decrease in mitochondrial as well as total cellular Nuc1pHA levels per se.

The addition of SR RS2) did not increase kcat for SR ΔRS2) phosphorylation but instead caused a small amount of inhibition.

As IAV infection alone did not lead to secretion of biologically active, Th1-polarizing, IL-12p70 but instead caused a priming of MDDCs, we chose to analyse the effect on this cytokine in greater detail.

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Somewhat surprisingly, we found that inactivation of Ndst1 does not affect branching morphogenesis or lactational differentiation, but instead causes a striking defect in lobuloalveolar expansion leading to insufficient milk production for survival of offspring.

Discontinuing a regulative treatment (eg, hemodialysis) does not generally result in an abrupt interruption of vital signs but, instead, causes a gradual lethal metabolic disorder.

Interestingly, where live bacteria are used, the enhanced inflammation and supposedly stronger anti-bacterial immune response in DUSP1-deficient mice do not facilitate bacteria clearance, but instead cause a higher mortality rate [ 73] or increased bacteria burden [ 74, 75].

Endosulfan and nonylphenol did not cause an initial (3 min) stimulation, but instead caused only a delayed single ERK phosphorylation peak at 30 min (which we designated slow-phase-only responders).

However, in contrast to its physiological role as promoter of angiogenesis, overexpression of Ang1 did not enhance tumour growth, but instead caused up to a 3-fold retardation of tumour growth (P = 0.003).

Bin Laden's killing should have ideally come as the most successful accomplishment in the decade-long war on terror, but it instead caused an unprecedented diplomatic row between the two countries The United States asked whether Pakistan was incompetent to trace the world's most wanted terrorist or it was simply complicit in providing him protection in Abbottabad, a well-guarded garrison town.

Attempting to speed up his progress, Schumann invented a finger-strengthening device that instead caused a partial paralysis of his hand.

The contact lens instead caused a reduction in retinal illumination experienced by the subjects as a general dimming across the retina.

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