Your English writing platform
Discover LudwigExact(5)
Glycyrrhizin did not affect cytokine expression of non-infected cells (data not shown) but inhibited expression of all cytokines investigated in H5N1-infected cells in a dose-dependent manner (Figure 2, Figure 3A).
For example, with patient samples IROC008 and IROC036, ascites fluid enhanced both CD8+ and CD4+ T-cell proliferation but inhibited expression of CD107a, CCL4, and IFN-γ (Fig. 1A, and data not shown).
This suggested that TGF- β1 may be beneficial for epithelial cell differentiation but inhibited expression of mesenchymal FGFs.
In addition, LED209 was not toxic to host cells, but inhibited expression of key virulence traits of EHEC pathogenesis (AE lesions and Stx production) (Rasko et al, 2008).
Also, SU6668 had no negative effect on Shh-induced GLI1 mRNA expression but inhibited expression of GLI1 up-regulated in response to TGF-β signaling (Fig. 6A b).
Similar(55)
In contrast, MT2A silencing did not modify cell viability but strongly inhibited expression of osteoblastic markers and differentiation process.
MATN3 protein not only maintained expression of anabolic genes including COL2A1 and ACAN in our experiments, but also inhibited expression of catabolic genes induced by IL-1β, including MMP-13, ADAMTS-4 and -5.
Nordihydroguaiaretic acid had no inhibitory effect on growth and survival signals such as tyrosine phosphorylation of the epidermal growth factor receptor or basal and growth factor-stimulated activities of extracellular signal-regulated kinase 1/2, p70s6k and AKT but selectively inhibited expression of cyclin D1 in the cancer cells.
Decrease in the expression of MDA5 or the related helicase RIG-I did not protect β-cells against PIC-induced apoptosis, but KD of MDA5 inhibited expression of the inflammatory mediators CXCL10, CCL2, CCL5, IFN-β and IL15.
Another study by our group revealed a different mechanism of PTTG1 suppression by T3/TRs, showing that T3 stimulation in TR-expressing hepatoma cells inhibited expression of specificity protein 1 (Sp1), thereby suppressing PTTG1, a direct transcriptional target of Sp1.
As Fig. 4A shows, overexpression of FBXW8 reduced endogenous expression of cyclin D1, but did not significantly change expression profiles of cyclin E. In contrast, FBXW7 inhibited expression of cyclin E, but not cyclin D1 (Fig. S1 [F]; [ref. 32]).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com