Both true protein and lactose yield was lower in period 1 with no effect in period 2. Supplementation of lactating cows with NIA reduced vaginal temperature, but had differing effects on milk production variables dependent on the period of the study which may be due to a more severe heat stress experienced in period 1 compared with period 2, and/or a more advanced stage of lactation in period 2.
67– 70 Seizure disorders of differing etiologies have differing effects on cognition.
Although there is certainly some decreased expression/activity of CYPs in cirrhosis, the mechanism of decreased hepatic drug metabolic clearance in vivo is more complex and may have differing effects on different enzymes.
As the processes of direct and indirect fracture healing are radically different, both physical modalities (e.g. ultrasound) and pharmacological agents may have differing effects on the different types of fracture repair.
Yet, the situation is complicated by the fact that different fatty acids have differing effects on the various lipoproteins that carry cholesterol.
There is evidence indicating different PIK3CA mutations have differing effects on PIK3CA signaling and AKT phosphorylation, and therefore may determine prognosis.
Although the various antipsychotics have differing effects, attributable to differences in their binding to dopamine, serotonin, histamine, glutamate, muscarinic and α-adrenergic receptors, all effective antipsychotics block D2 receptors including peripheral D2 receptors with varying potency and dose-dependent effects [ 34].
Drawing on recent management literature regarding organizational turnover intentions, we challenge the conventional view that mentoring generally leads to reduced turnover intentions, by testing a theoretical model that posits that different functions of mentoring have differing effects on turnover intentions.
In addition, the route of administration, oral vs intravenous, of vitamin C intake may also have a role in the efficacy and safety of vitamin C use in cancer patients as these different routes of administration have differing effects on plasma concentrations (Padayatty et al, 2004).
Thus, different degrees of hyperchloremic acidosis have differing effects on inflammatory mediator release as well as on NF-κB activation.
