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LY294002 inhibited AKT effectively, but had unpredictable effects on S6, confirming the nonselective activity of this broadly active PI3K-family inhibitor.
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In tests, brand new stirring bars did not affect reactions, but used bars had unpredictable effects that probably depended on the nature and amount of contamination.
The foreign presence had unpredictable effects.
It means there can be more mining, which is good for the economy, but it will have unpredictable effects on social change".
And bewildered Labour supporters are being besieged by Plaid Cymru and Liberal Democrat canvassers soliciting their second votes.But the new voting system might have unpredictable effects.
Putting aside the fact that the changes seen in CR are multifaceted and may not be easy to emulate with a single therapeutic, diet-related senemorphisms raise another serious hurdle: Because AL and CR aging are different processes with widely differing biochemistries, a drug which mimics one part of the CR pathway but in an AL background may have unpredictable effects.
Substituting the mouse C regions with human C regions in chAbs was a major advance in reducing the immunogenicity of mouse mAbs but our results show that this approach can have unpredictable effects on the thermodynamics of Ag-Ab complexes and the self-reactivity of chAbs.
There is a disorientation from ordinary processes that can have unpredictable effects on everyone concerned.
"Genome editing in human embryos using current technologies could have unpredictable effects on future generations.
Epistasis and linkage of genes likely will have unpredictable effects on IRM.
These preparations may contain variable amounts of thyroid hormone and can have unpredictable effects on the body.
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