A preliminary study has suggested coincidental occurrences of short-term SSEs and VLFEs southeast off Okinawa Island (Y. Asano, personal communication, 2013), but further study will be required to clarify the relationship among slow earthquakes in other regions.
So far, industry reaction seems to be positive toward the new guidelines, with support coming from automakers, security providers and others working on the private side of the equation, but further study will be required before we can assess the true impact the new federal policy will have on the progress of the industry overall.
The ability to use these lower doses could have major implications for the delivery, cost, and accessibility of anti-CD20 mAbs, but further studies will be needed to determine efficacy, optimal dosing schedule, and long-term safety in RA patients.
In this study we have focused on Th1 cells but further studies will identify whether the disease controlling effects of epicutaneous immunization on CCIA is additionally caused by an effect on Th17 cells.
In our model, robust polycythemia is induced by modest overexpression of JAK2 V617F in BM with two normal JAK2 genes, but further studies will be necessary to determine whether the phenotype is influenced by levels of normal JAK2.
A trend towards a greater fraction of Ad5-seropositive than Ad5-seronegative volunteers producing IL-17 in response to Ad5 empty vector before vaccination may be indicative of such a Th17 polarization, but further studies will be necessary to confirm this connection.
This family member might be expected to be neutral or anti-oncogenic, as E2F3b has been shown to preferentially bind pRb and repress S-phase genes in fibroblasts in vitro [21], but further studies will be required to address the oncogenic capacity of this E2F family member.
It even raises the possibility that TRKBT695I and TRKBD751N may act in a dominant negative fashion, and that wild type TRKB may also have tumor suppressing activity (or a dual function) in colon cancer, but further studies will be required to address these important issues.
We superficially investigated the regulatory mechanisms controlling SS in this model, but further studies will be required.
Taken together with earlier studies it is clear that LPL is present within insulin-producing cells, but further studies will be needed to understand its regulation and function.
Here also, endothelium-dependent mechanisms might contribute to the restoration of perfusion after treadmill running, but further studies will be required to reveal details of these mechanisms.
