In the UY1346 line, the insertion falls in the lilliputian (lilli ) gene in the reverse orientation, but could also allow forced expression of the upstream gene, NTPase, which encodes a nucleoside phosphatase.
But in MCF-7 cells, forced expression of Jab1 did not increase HIF-1α protein or HRE-dependent gene expression under either 20% or 1% O2.
Forced expression of arjN, but not arjC, could rescue the premature differentiation in asrij null mutant.
Although forced expression of EGR1 did not prevent osteosarcoma growth, forced expression of EGR1 prevented osteosarcoma cell invasion in vitro.
Forced expression of CLDN4 in the HEY cell line that does not endogenously express this protein produced similar effects.
Forced expression of KDM5C was mediated by retroviruses, and KDM5C was downregulated by shRNAs expressing lentiviruses.
Forced expression of full-length 3′UTRs conferred reduced protein expression.
Forced expression of EGR-1 induces Bax expression and apoptosis in pancreatic cancer cells.
Forced expression of Sox9 in MSCs promotes BMP2-induced chondrogenesis and suppresses BMP2-induced endochondral ossification.
Forced expression of p53 increased the mRNA levels of TGFβ1/2 (Fujiwara et al., 1994; Kannan et al., 2000).
