Sentence examples for but fail to activate from inspiring English sources

Possibly, these chromosomes are unattached but fail to activate the mitotic checkpoint due to diminished Mps1 activity.

We find that satellite cells are maintained in aged human skeletal muscle, but fail to activate in response to muscle attrition, due to diminished activation of Notch compounded by elevated transforming growth factor beta (TGF-β /phospho Smad3 (pSmad3).

We speculate that in the absence of aPKC activity, cells that downregulate NANOG and maintain GATA6, but fail to activate GATA4, may also undergo cell death.

In general, mice fed HFP diet show more pronounced transient induction of these pathways at the very beginning of the time course, but fail to activate them as efficiently as the mice fed HFBT diet at the late phase of the time-course (Figure 3).

Mice lacking caspase-1 (Casp1 −/− ) are viable but fail to activate and secrete IL-1 β.

The At80MD truncation protein may be able to compete with the endogenous AtMYB80 for binding the promoters of target genes, but fail to activate gene expression.

We find that CAgp130 is a potent Stat3 activator but fails to activate the MAPK cascade.

Internally applied Pb activates SK and BK channels more potently than Ca, whereas Cd is approximately equipotent to Pb with respect to SK channel activation, but fails to activate BK channels.

Similarly, overexpression of CaMKKβ caused activation of AMPK in HeLa cells, but failed to activate any of the ARKs tested.

MK-801 increased the promoter activity when the wild-type promoter region was transfected, but failed to activate the FOXO-Mut promoter.

Here, we show that the oncogenic mutant of Flt3 (Flt3-ITD), when localized at the endoplasmic reticulum (ER), aberrantly activates STAT5 and upregulates its targets, Pim-1/2, but fails to activate PI3K and MAPK signaling.