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Our findings suggest a strategy for the development of a safe but efficacious ZIKV LAV.
Few people in China in the nineteen-twenties and thirties observed Stalin's brutal but efficacious engineering more closely than Mao Zedong, then a restless young convert to Communism.
In 1962 the Food, Drug and Cosmetic Act was amended to require that any new drug should be not only safe but efficacious.
Thus, there is a need to develop less invasive, but efficacious treatments that can bypass the hurdles associated with crossing the BBB to treat brain disorders.
They are not effective when used for oral immunization but efficacious when administered by intranasal route.
Piperaquine is a bisquinoline compound, structurally related to chloroquine but efficacious against chloroquine-resistant parasites.
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Its widespread use was highly successful in reducing malaria mortality but less efficacious in reducing the number of cases.
Commercially available ocular drug delivery systems are effective but less efficacious to manage diseases/disorders of the anterior segment of the eye.
Posteromedial visualization was associated with morbidity but was efficacious in some cases and is strongly recommended when loose bodies are expected.
What may help clinicians remain focused on the larger picture while still safeguarding patients and themselves from multi-drug-resistant bacteria are less restrictive but equally efficacious precautions.
Our preliminary study with 30 participants shows that a considerable percentage of participants found Mathland to not only be engaging (83%), but also efficacious in the areas of collaborative learning (92.8%), problem solving (96.6%) and mathematics education (90%).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com