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Gabapentin is structurally related to the neurotransmitter gamma-aminobutyric acid (GABA) but does not modify GABA a or GABA b radioligand binding, it is not converted metabolically into GABA or a GABA agonist, and it is not an inhibitor of GABA uptake or degradation.
In fact, replacement of the native tryptophan residue with a phenylalanine significantly reduces Δ Hrc°′, but does not modify Δ Src°′.
By using the hyperinsulinemic-euglycemic clamp, they also showed that diacerein is able to improve insulin secretion but does not modify insulin sensitivity.
An example of a relatively soft electrophile is 15-PGJ2, which reacts with thiol groups on cysteine, but does not modify other nucleophilic amino acids [ 123– 123].
SAS PROC LOGISTIC, for example, prints a warning message but does not modify its estimation procedure, so that extremely large standard errors are reported.
Consequently, it reduces the blood levels of hormones regulating Ca metabolism during the laying cycle but does not modify the daily pattern of sex steroid hormone involved in ovulation [ 24, 25].
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The PI3K inhibitor LY294002 reduced the proliferation rate but did not modify the ACh cell content, whereas the PKA inhibitor H89 produced effects comparable to FLLL31.
Treatment A increased milk fat content by 6.5% but did not modify milk fat yield (because of a decrease in milk yield).
The nanoscale Al crystals lead to some hardening of the glass, but do not modify the good ductility of the material.
We have reported before that iONS applied during several months modulated central areas involved in non-specific pain control but did not modify the hypothalamic hypermetabolism found in CH [15].
BNa treatment significantly decreased ammonemia levels and intra-cerebral fluorescence in the BDL and BDL-NH3 rats (p < 0.04 for all) but did not modify the mean time of immobility.
More suggestions(19)
but does not alter
but does not update
but does not move
but does not think
but does not prevent
but does not affect
but does not fear
but does not guarantee
but does not venerate
but does not become
but does not rise
but does not tell
but does not get
but does not hold
but does not kiss
but does not promote
but does not understand
but does not have
but does not destroy
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