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Other insertions between the ZRS and Shh also showed expression, but differences were difficult to discern, as the limb buds stain appreciably at the 18 h time point.
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As it can be seen by looking at the waveforms (Figure 2), the P1 and N1 differences were difficult to separate because they occurred in adjacent time-windows.
Initially, these differences were difficult to explain.
Significant differences were difficult to detect at the early time points.
Gender differences were difficult to explore in Stage 2 because, by chance, most of the participants were female.
The collection of 700 poems in this language, compiled by Hāla under the name of Sattasaī ("The Seven Hundred"), tends to be simpler in imagery and in the emotion portrayed than their Sanskrit counterparts, but essential differences are difficult to pinpoint.
Mice provide high-throughput models including mutants lacking or expressing genes of interest, but interspecies differences are difficult to overestimate.
The ferret serum HAI assay works well to distinguish major drift variants, but moderate differences are difficult to define reliably (26).
In the height image (Fig. 1a), the measurement mode is strictly related to height proportions and reveals the actual 3D topography, but small height differences are difficult to discern in this imaging mode.
These differences are difficult to interpret but might be due to different life styles, socioeconomic status or cultures [ 7, 21- 23].
Metal-ligand binding changes substantially for different ligand classes, and these differences are difficult to accommodate with a single set of descriptors.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com