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Three of the five patient-derived OS lines exhibited apparent expression of LPAATβ while other two lines showed weak but detectable expression of LPAATβ (Fig. 1B).
As shown in Fig. 1A, hTERT transcripts were not observed in control MRC5 cells while tranylcypromine treatment induced a weak but detectable expression of hTERT mRNA.
Weak but detectable expression of MITF and melan-A was seen in MDA-MB-231 cells, and tyrosinase (TYR) was nearly absent in MDA-MD-231 cells [Figure 2 II), lane 4].
For those truncations that allowed low but detectable expression of the μ gene,, e.g., enhancer segments Ep'q'r' (#651) and E-q'r's' (#654), the gene structure did not uniquely determine the level of μ expression.
Jurkat E6.1 T cells had little to no detectable CD4 expression whereas the majority of HuT78 T cells had a low but detectable expression of this protein (Table 2).
The reduced, but detectable, expression of Kirrel-2 in the transgenics thus indicated that dnRAR did not abolish CNG channel function completely.
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Reduced, but detectable expression levels of ladA, larA and xdhA were observed in the Δ araRΔ xlnR strain on l-arabinose and l-arabitol, while xdhA was also expressed on d-xylose in the Δ araRΔ xlnR strain.
Obviously, however, alternative splicing allows a strongly reduced but still detectable expression of the wild type allele and this expression varies between different tissues (Figure 1B).
Second, we cannot fully rule out the possibility that the low, but still detectable expression of the AT receptor in the CA (Figure 6A) may mediate the allatotropic activity of its ligand, though we could not detect any allatotropic activity of AT using our in vitro CA culture (data not shown).
In contrast to the adjacent non-malignant kidney tissue, we were able to demonstrate a heterogeneous but constantly detectable expression of CXCR4 antigen in malignant tissue.
Performing Western blot analyses of CXCL13 and CXCR5 expressions on lysates of six randomly selected breast cancer samples and four healthy breast tissue samples, we observed a weak but constantly detectable expression of the chemokine receptor CXCR5 in tumour samples, whereas protein expression of this chemokine receptor was not detectable in the healthy samples analysed.
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