Whereas, wild type HPV90 E6 induced a slight MG132-sensitive decrease in p53 levels and a slight, but detectable decrease of p53 signal in single transfected cells (Figure 4B); the K16N mutation of HPV90 enabledled it to fully degrade p53 in Western blot-based assays (Figure 4A) and to turn off p53 signal in single transfected cell assays (Figure 4B) as efficiently as HPV16 E6.
Sowers et al. (2002) observed increases in blood lead from the 20th week to delivery in African Americans (1.20 1.49 μg/dL; an increase of 24%) and Hispanic Americans (0.99 1.32 μg/dL; an increase of 33%) but a barely detectable decrease in blood lead of 0.03 μg/dL at delivery for Caucasians.
The abundance of calreticulin transcript in Ar. subalbatus responding to B. malayi infection showed no detectable change at 1, 3, 6, and 12 hours, but the transcript showed a detectable decrease in relative abundance at 24 and 48 hours post infection.
However, this appears unlikely, as no detectable decrease in Rsp5 levels was detected in a ubp2Δ mutants (M.L.; unpublished observations), and Rsp5 has not been reported to be (auto)ubiquitinated in vivo.
A significant reduction in fluorescence recovery was also observed in the bleached pan-IP3R-knockdown cells, but not in the IP3R isoform-knockdown cells, except for a detectable decrease in the recovery rate observed in IP3R-1 deficells cells.
At low levels (<500 ppb) H2S addition does not cause a detectable decrease in activity during 5 10 days of exposure to H2S.
At the dose used, SERPINA3K did not induce any detectable decrease in cell viabilities in Müller cells.
No detectable decrease in growth was observed when R. maritima was cultivated in the absence of salt.
In the heterozygous state (Tnnt2+/−), there was a mild decrease in Tnnt2 mRNA, with no detectable decrease in total cTnT protein, and a normal cardiac phenotype.
