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Notably, STAT3 has been demonstrated to activate or repress its direct target genes in NIH 3T3 cells, with OSM treatment increasing six of 18 direct target genes specifically tested, but decreasing expression of ten of these 18 direct target genes [ 53].
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We found increased expression of DKK2 but decreased expression of DKK1 in Ewing family tumor (EFT) cells.
Treatment at 16°C resulted in an increase in the expression of ath-miR156, ath-miR161.a2, ath-miR166 and ath-miR169, but decreased expression of ath-miR163, ath-miR172, ath-miR396∼399 and ath-miR830 [13].
Moreover, decreased levels of HOTAIR expression resulted in significant increased expression of E-cadherin but decreased expression of N-cadherin and vimentin in gastric cancer cells.
qRT-PCR analysis showed that B-deficient roots had enhanced expression of LRP, but decreased expression of sulfate transporter (Table 3).
The western blotting results showed that SeC treatment for indicated time notably increased expression of Bax, but decreased expression of Bcl-2 in a time-dependent manner.
RT-PCR assays from colon showed that T. crassiceps-infected mice displayed increased expression of Arginase-1 but decreased expression of iNOS compared to DSS-treated uninfected mice.
In tumors formed by these cells, GLA elevated expression of E-cadherin mRNA but decreased expression of vimentin mRNA (Fig. 4a,b).
Among genes implicated in migration/cytoskeleton/ECM, we found increased expression of Plek, Fermt3 and Ly86, but decreased expression of Col9a3, Lamb1-1, St3gand and Limk1.
In the presence of NP-treated mDCs, T cells showed increased levels of IL-13 but decreased expression of interferon-γ.
Of note is the presence, but decreased expression of detectable p96 and p67 isoforms in the ductal carcinoma in situ (DCIS) sample (No. 11).
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