Whereas AZT alone produced no striking effect on secreted IL-8 levels, AZT pretreatment resulted in an unexpected, but consistent, increase in the levels of secreted IL-8 after SMM treatment (Figs. 6B and 6C).
In fact, AZT, after an initial inhibition of NF- κB activation with respect to control, induced a transient, but consistent, increase in NF- κB-binding activity.
While small but consistent increases in the average life span are not going to lead to immortality, he says, there is no reason to assume that we know where progress will stop.
However, our laboratory measurements showed that N application had no effect on Rh in mineral soil, but a small but consistent increase for 10 weeks when the mineral soil had an LFH (litter-fibric-humus) layer on the surface.
In Ribi, there was a small but consistent increase in gp120-specific antibody titer of a gp120ΔC1/C5(C3d)2 prime followed by two gp120ΔC1/C5 boosts compared to three inoculations of either the gp120ΔC1/C5 proteins or the gp120ΔC1/C5(C3d)2 proteins alone.
Only a slight but consistent increase in TCR-mediated phosphorylation of p38 was noted (Figure 3A).
There was a mild but consistent increase (about 2-fold) in the expression of these genes in Cby−/− lungs in comparison with Cby+/+ controls (Figure 1B).
Serum deprivation led to a slight but consistent increase in PEG10-prom−1910 reporter activity in all assays (Figure 5B and 5C).
Interestingly, after Aβ exposure, there was a slight but consistent increase in firing frequency just before the decline of spontaneous activity.
Surprisingly, the calculations for Δhat1 and Δgcn5 cells showed that the addition of STARs generated modest, but consistent increase in telomeric silencing.
