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First, we showed that FRDA cells under basal conditions had a small but consistent elevation in SOD activity and confirmed a reduction in reduced glutathione, indicating that they had to cope with abnormally high levels of superoxides and derived peroxides.
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In patients with continuous spinal fluid pressure monitoring, small but consistent elevations in spinal fluid pressure are associated with oxygen desaturations in patients with sleep disordered breathing.
Splenocytes from PsaA-BLyS immunized mice exhibited elevated levels of secretion of IL-2, IL-4 and IL-5, and a very modest but consistent elevation of IFN-γ following in vitro stimulation with PsaA.
Moreover, an analysis of the transcriptome of treated monomorphic cells revealed a modest but consistent elevation of a number of transcripts known to be regulated during the development to stumpy forms in vivo.
After one week, rabbits exhibiting a consistent elevation in blood glucose (> 350 mg/dl) remained in the study.
The consistent elevation in mortality based on a weekend admission however implicate a more central structural or process measure, which is more fundamental than the role of trainees.
Figure 2A shows the significant and consistent elevation in pressor response to air stress in the Sry1 group (41 mmHg) compared to controls (28 mmHg) at days 8 and 22.
A consistent elevation in plasma levels of four cardiac miRs (miR-1, -133, -208a and −499) was observed in AMI patients within few hours after the onset of symptoms for infarction [ 172- 181].
Together with the pan-cancer heat maps presented earlier, these results illustrate that CIMP+ tumors show consistent elevation in average CGI methylation levels among multiple cancer types, even though an important fraction of this hypermethylation is distributed in tissue-specific patterns.
Small but consistent elevations mostly within the normal range in lipase and amylase, not accompanied by other signs or symptoms of pancreatitis, were observed over time with liraglutide treatment in obese and type 2 diabetic populations.
In the current study, measurement of plasma dUrd concentration showed that pemetrexed administered at doses of 400 700 mg m−2 produced consistent elevations in plasma dUrd, suggesting that plasma exposure to pemetrexed was sufficient to induce TS inhibition in patients.
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