However, no activation was seen when Bak had been targeted at the same time, suggesting that Bax activation is secondary to Bak activation but Bax cannot be activated in its absence.
Combined with Kringle V, the inactive protease domain of Apo(a) is structurally similar to the corresponding part of plasminogen (Kringle V plus active protease) while cannot be activated by tissue plasminogen activator and urokinase plasminogen activator [ 36].
In principle, dosage-varied networks that cannot be activated beyond their basal activity levels or networks that always stay 'ON' irrespective of the inducer levels can also be classified as dosage-compensated, but they lack the ability to act as regulatory networks against external physiological signals.
On the other hand, if the central cholinergic system has deteriorated, then it cannot be activated and cannot compensate for the peripheral activity of inflammatory processes.
This is more of a long-term pickup since Brown cannot be activated until Nov. 10, but he has begun practicing with the Giants so he's worth a look if you have room on your bench.
(A ) In discs from larvae of the genotype indicated maintained at 17°C the Gal80TS repressor blocks Gal4 activity, thus the UAS vectors cannot be activated.
In contrast to HGF, H. pylori is an activator for all seven transcription factors because ERK1/2 cannot be activated via Grb2-Sos1-Ras-Raf1-MEK and therefore only through the positive pathway PKCα-Raf1-MEK-ERK1/2 (the latter is also functional with HGF).
Using this information, Langemeyer et al. create a human Rab protein that cannot be activated by the GEF from the bacteria that cause Listeria, but can still be activated by its normal human GEF.
Williams cannot be activated because he was replaced on the roster by Jack Haley.
Moreover, in contrast to PARP2, the E545A mutant of PARP2 cannot be activated by PAR (Supplementary Figure 4E).
