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OPase activity was present in all 37 tumor samples, but at variable levels.
Using the standard conditions, all the truncated gp91phox proteins are expressed but at variable levels, as detected by western blotting (Figure 2B).
We found constitutive STAT3 phosphorylation in most of the investigated cell lines, but at variable levels.
However, when retinal cells are transformed, high MDM2 expression is consistently expressed, but at variable levels [ 7]; thus other factors may affect p53 tumor surveillance.
Fgfr2 expression was detected in 9/10 ICM cells randomly selected from IOD embryos 24 hours after 4-OHT administration, but at variable levels (Fig. 2E).
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PCR on cDNA from a panel of human tissues revealed that the two splice forms are widely expressed, with the longer form being ubiquitous and the shorter form being present in many but not all tissues at variable levels.
The MDR1 mRNA was not detected after 22 cycles of PCR in the 10 gastric cancer cell lines but could be detected at variable levels after 35 cycles of PCR with the exception of SNU-16, suggesting a significantly low level of MDR1 mRNA expression in the gastric cancer cells tested.
We identified modules of highly coexpressed genes, some of which are restricted to a single lineage but most of which are expressed at variable levels across multiple lineages.
E-cadherin was observed at variable levels in the cytoplasm and nucleus in all tumor samples but not within the cell membrane.
Conversely, AMPKα2 is expressed at variable levels in colon cancer cells.
In addition, NK cells can also express TLRs, at variable levels, and thus downregulation of TLRs might impede the functionality of NK cells directly47.
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