Agreement between methods against the reference method are also expressed in a percentage (LOA%); that is, at low CO a small error and at high CO a higher error is observed.
Most sequencing technologies have a higher error rate at mononucleotide stretches of DNA.
The simulation further showed that ustacks robustly identified SNPs, except at a high error rate and low depth of coverage, or when confounded by repetitive sequences.
At a low dose, the errors grow very large when the defocus is small, but even at a higher dose, errors due to noise become present when the defocus is too small.
Populations optimized at a slightly higher error rate (μ1 = 0.002) experience a substantial increase in their adaptive ability (Fig. 3; Table 3).
The worst level of noise (30 dB) results in 11% to 22% error for damage intensities higher than 25% and a much higher error at lower damage intensities.
At even higher error rates, the average protection is not sufficient for keeping the profile above the message size floor, and an increased protection rate is requested for correct operation of the algorithm.
These pools are over one order of magnitude larger than those predicted at the higher error rate of 5×10-4 5×10-4present point mutandons in 10-13% of the genomes.
On the other side, at higher error rates, the profile climbs over, at the beginning, and submerge below, toward the ending, the average protection level.
At higher error rate targets, this is less critical, and a channel-aware scheduler can even benefit from the at times slowly changing interference levels (cf. Figure 4), and can therefore make more qualified scheduling decisions leading to a higher throughput.
