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We speculate that deletion of amino acid 617 disrupts not only the eIF5B interaction but another interaction as well that is involved with piRNA processing.
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The violation is thought to be related to something called the weak nuclear force, but effects of another interaction called the strong force confuse matters in kaons.
For example, the interaction between GR [NR3C1] and Nur77 [NR4A1] is mentioned only once in the literature, but there is at least another interaction (e.g GR [NR3C1] – Nurr1 [NR4A2]) between the NR3C and NR4A phylogenetic groups, that also has only one source of evidence.
Every comment is another interaction with an article.
Not stage-ready, but another step toward interaction – Quentin Hardy Vice's Shane Smith on What's Wrong With Canada, Facebook and OWS forbes.com | Vice CEO Shane Smith on Mark Zuckerberg: "the Stalin of Facebook is his own worst enemy".
For those PPI where orthologues exist for both interacting proteins in another species, but no interaction is known between those proteins in that other species, a conserved interaction (an interologue) were predicted.
Overall, our results are consistent with a model of CLIC function in which covalent binding of glutathione does not occur spontaneously but requires interaction with another protein to stabilise the GSH binding site and/or transfer of the ligand.
The close proximity of these cells naturally suggests that they interact with one another, but these interactions are just beginning to be characterized.
It is unclear if this "side-on' interaction might be another less-known but ancient interaction feature of the β-GF domain or has convergently evolved in the superantigen/toxin-type and strepto/staphylo-kinase-type domains on one hand and it the 4-stranded Ig-binding domain on the other.
This suggests that the two interact, and some support for this is lent by a recent study of GTPase activating proteins, that reported that TBC proteins do not directly interact with Rab proteins, but require another protein-interaction domain, confirmed by truncation mutant analysis for the case of a C-terminal Ankyrin domain [ 33].
Interaction scores were not penalized for their apparent absence in another species in which the orthologues were conserved but no interaction known.
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