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As the current data showed that Gβγ dimers alone are ineffective in the co-immunoprecipitation with PKD, hence, our findings not only demonstrate the crucial role of PLCβ2 for the effective binding between Gβγ dimers and PKD, but also implicate that only specific Gβγ dimers are capable of interacting and activating PKD in the presence of PLCβ2.
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This not only demonstrates a true prognostic value for BCAR3 but also implicates that loss of BCAR3 expression may be involved in breast cancer progression.
The results also implicate that high cyclin D1b may be a negative predictor for the effect of adjuvant treatment with 5-FU/LEV.
It could also implicate that anatomical changes in the bone formation or blood supply of the femoral head – increasing its sensibility for trauma – contribute to the etiology of LCPD.
Almost exclusive expression of the V2R protein in renal collecting ducts warrants specificity and safety of the drug but also implicates that extrarenal PKD manifestations will not be targeted.
Recent studies not only confirm the association of APOE with longevity in different populations, but also implicate several other pathways that may influence longevity including nitric oxide production, inflammation, immunity, and DNA damage response and repair.
These results also implicate that PDF may be a potential anticancer drug to head neck cancer.
These results also implicate that manipulation of antigen delivery will facilitate the design of improved vaccination strategies to persistent viral infection.
These data also implicate that bevirimat and PF-46396 interact differentially with this putative pocket.
Furthermore, our results also implicate that downregulation of MAD2 may be an indicator for identification of cisplatin resistant TGCT patients.
Our findings also implicate that Id-1 may be a potential target for the development of novel strategies in the treatment of ovarian cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com