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Furthermore, cell labeling and extracellular matrix expression assays demonstrated that the transplanted hESC-MSCs not only contributed directly to tendon regeneration, but also exerted an environment-modifying effect on the implantation site in situ.

Rubiyunnanins C-H (94 99) and RA-V, RA-I, RA-XXIV, RA-XII, RY-II not only exhibited cytotoxicities against the same cell lines with IC50 values ranging from 0.001 to 56.24 μM, but also exerted inhibitions against NO production in LPS and IFN-c-induced RAW 264.7 murine macrophages with IC50 values ranging from 0.05 to 12.68 μM [55].

The actual functional impact of NRs on gene expression is not only triggered by ligand binding to the receptors but also exerted through an interaction of the NRs with co-regulatory proteins, leading to a consecutive modification of chromatin structure.

Ebola virus outbreak in West Africa not only triggered a grave public health crisis, but also exerted and induced huge mental distress on medical staff, which would negatively influence epidemic control and social rebuilt furthermore.

This was in contrast to the PI3K inhibitor wortmannin [ 44], which blocked matrix vascularization (Fig.  5a) but also exerted a toxic effect on normal CAM vessels causing vessel occlusion and hemorrhages already 24 h after implantation (Fig.  5b).

Previous studies utilized phage display peptide libraries to isolate and identify peptides that not only specifically bind to cell receptors in a cell-specific manner, but also exerted biological effects on the target cells [ 18– 218.

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That gay women not only exist but also exert considerable sway has only begun to be acknowledged.

"Soundings" not only details its subject's monumental work and entanglements with gender bias but also exerts thoughtful pressure on the boundaries and biases of this literary genre.

Testosterone is not only a factor in libido but also exerts essential effects on the anatomical and physiological substrate of penile erection.

Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonist, rosiglitazone, not only improves insulin resistance in patients with type II diabetes but also exerts a broad spectrum protective effects in variable animal models of neurologic or cardiovascular diseases.

This study further reveals that partnering can not only directly facilitate organizational capability and risk management but also exert its influence on risk management through enhanced organizational capability, thereby improving project performance.

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