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Although slightly larger than predicted the N-term protein was detected in a processed form in vivo, thus not only demonstrating initial translation of the ORF1 polyprotein but also activity of the viral encoded protease.
Although slightly larger than predicted the N-term protein was detected in a processed form in vivo, thus not only demonstrating initial translation of the ORF1 polyprotein but also activity of the viral protease.
From the functional analysis of Tfn endocytosis (Figure 6A), we conclude that not only localization to endosomes but also activity of A-RAF kinase in the mitogenic cascade on endosomes are a prerequisite for the translocation of Tfn-positive endosomes to the pericentriolar region.
Antipsychotic medication may not only affect the function of respiratory chain complexes, but also activity of the pyruvate-dehydrogenase complex [ 14].
Reinforcing this circuitry, the death associated protein kinase 1 (DaPK1), a tumor suppressor found hypermethylated in tumors and a crucial inhibitor of Pin1 isomerase activity (Lee et al, 2011), was shown to be repressed by N1-ICD (Li et al, 2008), delineating a possible scenario in which N1-ICD boosts not only expression but also activity of Pin1.
Therefore, the severity in our patients not only comprises the extent of lesions but also activity of lesions with progression and therefore, approaches the characteristics of the patients reported by Lecewicz-Torún et al. [ 10], who also reported a decrease of T-cells in peripheral blood in psoriasis (expressed as percentage of total PBMC).
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Constantly alert to the question of function, this book recreates not only rituals of the past but also activities of the present, from the coronation of the doge to the legendary Pink Floyd concert of 1989, with much fanfare in between.
Our observation that the mutation spectrum in the presence of MBD4tru does not specifically show an increase of C to T transitions at methyl-CpG sites, but instead increases mutation frequency across the entire spectrum, implies that MBD4tru not only inhibits wtMBD4 activity at methyl-CpG sites, but also activities of the other glycosylases at least, and perhaps also other DNA repair pathways.
As a consequence, PAV integrates not only diaphragm activity, but also the activity of extradiaphragmatic inspiratory muscles such as scalenes or parasternal intercostal muscles [ 39].
Heterologous PCX cellulase activity was affected by not only the high-mannose glycosylation pattern, but also the activity of intracellular trafficking systems of S. cerevisiae.
Finally, we also need to evaluate not only the expression of iNOS but also the activity of this enzyme, as well as the evaluation of constitutive nitric oxide sintase isoforms.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com