Sentence examples for but abrogated from inspiring English sources

Acute DSS colitis did not result in an anion secretory defect, but abrogated the sodium absorptive function of the mucosa.

A V326N substitution in the amyloid-forming region conserved secondary structure and ligand binding, but abrogated formation of amyloid fibrils in soluble Als5p and reduced cell surface thioflavin T fluorescence.

However, in monocytes E2 had no effect on promoter E usage, but abrogated the usage of promoter F. These findings allow us to conclude that through distinctive changes in promoter usage with E2 treatment, macrophages are able to up-regulate ERα expression with E2 treatment, whereas monocytes do not.

HIF-1α gene deletion had no effect on NSPC survival at 24 hr following 2 hr OGD (96.8 %±8.5%% vs. 101.6 %±6.7%%, HIF-1αwt/wt vs. HIF-1αΔ/Δ, respectively, ns, n = 4; Figure S4), but abrogated the neuroprotective effects of NSPC conditioned media (Figure 5D).

Sirtuin 6 shRNA did not influence the size of the colonies (Fig. S6b), but abrogated the promoting effect of TGF-β1/H2O2/HOCl TGF-β1/H2O2/HOClion (Fig. S6colony

Similarly, in AR positive cell lines LNCaP and DuCaP AMPK was activated after 24 h of treatment but abrogated after 96 h (Additional file 2: Figure S1B).

But abrogating the rights and privileges we hold dear, and for which many have fought and died, is not the answer.

This combination would preserve the beneficial effect of VEGF on ECs but abrogate its detrimental effect on SMC apoptosis.

Consequently, imatinib does not eliminate bcr abl oncoprotein expression but abrogates its function and therefore reduces the relative fitness of cancer cells.

Conversely, N-acetylcysteine protects normal cells from the cytotoxic effects of anticancer drugs by preventing the elevation of intracellular H2O2 through its reductive properties, but abrogates the effectiveness of chemotherapeutic drugs.

IL-1β suppressed isoproterenol-induced UCP1 mRNA expression in C3H10T1/2 adipocytes, and this effect was partially but significantly abrogated by inhibition of extracellular signal-regulated kinase (ERK).