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Western blotting also revealed no change in the expression of Bcl-2 but a substantial decrease in XIAP and Mcl-1 with Tenovin-6 treatment.
Western Blot analysis revealed similar expression and phosphorylation of p65, c-Jun, Stat3, and ERK1/2, but a substantial decrease in phospho-p38 protein levels was evident in TgS100a8a9 hep as compared to Control hepatocytes.
A Finnish investigation found PCT concentrations to be higher in more severe cases of advanced sepsis, but a substantial decrease in concentration was a more important survival predictor than were absolute values [ 13].
Attempts to enhance diagnostic scores by combining FOB with one or more caregiver-reported symptoms or anemia resulted in improvements in specificity but a substantial decrease in sensitivity, and a reduction in AUC score in comparison with FOB alone (Supplemental Table 1).
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Whiplash injuries, which from an emergency point of view are regarded as minor injuries (AIS 1) have been frequently present, but show a substantial decrease, probably associated with the penetration of better neck restraints in the vehicle fleet and frequent building of roundabouts in recent decades.
Also, it enhances the plastic strain ahead of the notch tip but leads to a substantial decrease in the opening stress.
A comparison over time of outpatient visits and inpatient admissions for malaria showed that total visits for malaria were relatively similar from 2005 through 2007, but there was a substantial decrease in malaria cases by 2008.
Currey et al. (1995) investigated the effect of formaldehyde on the mechanical properties of human bone, reporting quasistatic loading tests that were almost unaffected by fixation but also noting a substantial decrease in impact strength.
Notably, children with the GSTP1 Ile105VandVal105Val and TNF GA/AA genotypes exposed to high levels of NOx not only had the highest risk of sensitization but also showed a substantial decrease in their PEF values (on average, −27.8 L/min compared with those exposed to low levels).
Incorrect conditioning induces a small amount of bias into the RB2 estimator but is accompanied by a substantial decrease in MSE.
Whereas a robust signal for phosphorylated PKA substrates was seen in the majority of cells, neurons expressing PA PKI, but not PA PKI C450A, showed a substantial decrease in PKA activity.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com