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But a second study published in today's New England Journal casts doubt on the idea that estrogen without progestin could protect the cardiovascular system.
The first, in 1998, found that the massive (2,600 km2) Tucurui reservoir emitted 76 tonnes of methane per km2 and 3,808 tonnes of carbon dioxide each year; but a second study last year put the figures at a mere five tonnes of methane and only 2,378 tonnes of CO2.
But a second study in the same issue suggests that large doses may be required to achieve clear-cut benefits.
But, a second study of 179 families could not replicate this result [ 31].
One study described that overexpression of Wt1 in myoblast cells did indeed inhibit their differentiation (Miyagawa et al., 1998), but a second study could not confirm this (Tiffin et al., 2003).
One study on house mice supports this hypothesis (Ramm and Stockley 2009a), but a second study found no support (Ramm and Stockley 2009b) and a third study found that males reduced the number of sperm transferred when mating in the presence of a rival male (Ramm and Stockley 2007).
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One study 25 focused on the positive association (P = 0.003) between weight loss and the homozygous variant (either G/G or A/A) G148A of PNMT (phenylethanolamine N-methyltransferase) encoding for an adrenal enzyme catalyzing the conversion of norepinephrine to epinephrine 55 but, in a second study, this result was not confirmed.
A similar peak was seen in methylation profiles of A. thaliana embryos and endosperm in one study [ 51], but not in a second study [ 58].
Several other molecules have been assessed in good quality studies that met the REMARK inclusion criteria, but do not have a second study available for pooling.
It has not commissioned a second study but the figures from Nielsen suggest the gambling industry continues to splash out to reach as many viewers as possible.
While in one study ADC was lower in recurrent cancer than in benign tissue after radiotherapy, a difference was only found before but not after radiotherapy in a second study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com