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With the same data set, but a reduced sample size (6,436), they reported two years later a prevalence of 24.1% [ 19].
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Insulin sensitivity was assessed by the frequently sampled intravenous glucose tolerance test (FSIGT), using a reduced sampling protocol [ 17].
Monthly or seasonal time series are often made available, but suffer from reduced sample numbers that increases the uncertainty in the data.
Like DHSs, ATAC-seq also finds areas of open chromatin, but has a faster workflow and reduced sample input, and we expect it to be useful for epigenomic analysis of large numbers of patients in future studies.
Samples were analyzed in a 2-step procedure so that an initial screening reduced sample numbers.
However, the main advantage of utilizing a prior model for the fraction defective is not necessarily reduced sample size but improved assessment of the true sampling risks.
Later developed procedures reduced sample preparation to a single precipitation step or an ultrafiltration step prior to analysis.
This procedure reduced sample size; thus, an alpha of.05 was used.
That said, this restriction does limit the generalizability of the results obtained from the reduced sample.
In Table 2 resulting drop-out rates and reduced sample sizes are stated.
The results are consistent in both the larger sample containing pair-mates and the reduced sample.
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