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By 2009, this figure had fallen to 8.4% – still unacceptable, of course, but a dramatic reduction nonetheless.
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First, Molino cavefish do not display enhanced VAB, but have a dramatic reduction in sleep compared to surface fish.
Inactivation of the Nrf2 gene is compatible with life (Chan et al, 1996) but leads a dramatic reduction of the resistance to oxidative stress (Li et al, 2004).
This mutation does not abolish D-glucose uptake, but causes a dramatic reduction in the D-glucose affinity and thus also a reduced inhibition of D-xylose transporter by D-glucose.
Indeed knockout of mfn2 has no effect on the number of dopaminergic SN neurons but causes a dramatic reduction in the number of dopaminergic nerve terminals in the striatum of affected mice, an accompanying reduction in striatal dopamine levels and locomotor disturbances (Lee et al., 2012).
Cation-modification has little effect on DMMP solubility but results in a dramatic reduction in DMMP diffusion constants.
In contrast, the D905R mutation not only prevented the G9a-dependent de novo DNA methylation during RA-induced differentiation of mESC, but also caused a dramatic reduction in global cellular levels of H3K9me2 in the undifferentiated mESC.
In a previous study we could demonstrate that inhibition of class I and II HDACs with TSA leads to an increase in neurogenesis in the developing cortex, but results in a dramatic reduction in neurogenesis in the medial and lateral ganglionic eminences (GE) of the embryonic forebrain [ 27].
But it still constitutes a dramatic reduction on government money spent on the poor – distorting a budget that ordinarily rises and falls depending on the performance of the economy.
G.A. Yeah, but [it's not a dramatic reduction].
A prospective examination could reveal stronger postponement effects, but would also lead to a dramatic reduction in the number of cases.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com