Recruitment into this intensive and burdensome study was difficult resulting in small numbers of patients.
Finally, our study measures only a few attributes of care that can make care burdensome; the study also has no information regarding post-discharge occurrences, such as adherence to discharge instructions, the adequacy of follow-up ambulatory care, or unintended hospital readmissions.
Participation in the side validation study was burdensome to the study subjects: a technician had to come every day to change the sampler filter, and the sampler itself was noisy.
However, because such assessments may require up to 30 minutes for administration and scoring [ 18] they are impractical for clinical use and burdensome for research studies.
The problems with personal measurements are that they are costly and time consuming, they can be burdensome for the study participants, and suitable monitoring devices are not available for all pesticides and pathways of interest.
Given that one of employers' chronic complaints about wage subsidies is that they are administratively burdensome and that some studies have found that employers do not claim subsidies for a large proportion of their eligible employees, this could improve the take-up rate of the subsidy.
A burdensome disadvantage to genetic studies of postzygotic isolation is that the phenotype of interest, sterility or inviability, precludes direct genetic crossing schemes.
Lower incomes, lack of insurance, and poor health all contribute to difficulty paying for health care, findings consistent with previous studies of burdensome costs [ 3, 4].
Some of the public health nurses particularly felt that the recruitment of the intervention group and the paperwork of the study were burdensome, mostly because of their hectic pace of work.
