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Shorter timespan gains could be perceived as worthwhile for therapies with less burdensome side effect profiles.
Immunosuppressive therapies have burdensome side effects which may lead to sub-therapeutic dosing and non-compliance.
Moreover, some commonly used treatments may predispose RA patients to burdensome side effects [ 9, 10] and increased mortality [ 11].
Our results demonstrated that the occurrence of diarrhoea was frequent and considered a burdensome side effect of the CT colonography preparation.
Surveys have shown that fatigue is among the most frequent and burdensome side effect of chemotherapy and results in impaired or diminished physical activity.
This means that, for several months, the patients are not offered regular exercise despite reduced functional capacity, impaired QOL and burdensome side effects.
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At the same time therapies that improve survival time are often accompanied by burdensome (toxic) side effects.
Secondary outcomes included total pain and burden of CT colonography (5-point scale), the most burdensome aspect and side effects.
Until recently, the available forms of treatment were not 100% effective and were associated with burdensome injections and side effects [ 35].
"It's a lot better for morale to have people teaching kids to read for a couple of hours a week than sending them to shoot paintballs at each other," says Jason Tanner of Community Service Volunteers, the country's largest umbrella group.Another answer is to make volunteering less burdensome to both sides.
"Our new Lemon for Business offering is designed to eliminate tiresome tracking and endless expense report paperwork that is burdensome for all sides of the reporting process," Casares said in a press release.
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