Sentence examples for burdened with difficulties from inspiring English sources

However, despite many advantages, traditional transgenic models for breast cancer are also burdened with difficulties in early detection and longitudinal observation of transgene-induced tumours, which in most cases are randomly located and occur at various time points.

In circumstances in which long time roles and patterns of authority are reversed and confidences are sometimes breached, making decisions for a family member is burdened with difficulty.

Before going further, we need to clarify the use in this study of the two terms in focus: "information" and "awareness", as they are both burdened with some difficulties.

Her music now comes burdened with expectations.

Women were still burdened with domestic drudgery.

Myanmar is burdened with antiquated laws.

We are burdened with hindsight.

There is the fear, and then there is the financial burden, isolation, difficulties with intimacy, and shame that comes with living with it in a world where almost no one recognizes its existence.

Because there is the fear, and then there is the financial burden, isolation, difficulties with intimacy, and shame that comes with living with it in a world where almost no one recognizes its existence.

But the hell with difficulties.

But this, too, is fraught with difficulties.