"The perception in our community is that Longwood is bearing the burden of the development without enjoying the benefits," Dr. Gerstenlauer said.
While the role of amyloid burden in the development and progression of clinical symptoms remains unclear and under active investigation, plaque clearance has been a key target of numerous clinical trials.
"A failure to improve our grid will be a significant burden for the development of new renewable technologies," says Vinod Khosla, founder of Khosla Ventures, a venture capital firm in Menlo Park, CA, that has invested heavily in energy technologies.
"Racial exclusion has been a burden on the development of public policy related to black Panamanians in general and Colón in particular," said Jorge Luis Macías Fonseca, a professor of history at the University of Panama in Colón.
We first circulated the shorter list of indicators to 33 members of a review panel established previously by Lifting The Burden for the development of cross-cultural management aids [22].
Catalonia, an autonomous region in Spain, has actively begun to advocate more vigorous efforts to decrease the sepsis burden through the development of an Inter-hospital Sepsis Emergency Code, operational between the Catalan Health Service (CatSalut) and seven local medical societies [13].
Adopting the BCS-based biowaiver system would reduce the regulatory burden in the development of new generic drugs and mitigate potential risks for healthy volunteers participating in clinical studies.
In early phase pneumonia, protective ventilation with lower tidal volume and higher end expiratory pressure has the potential to reduce the pulmonary bacterial burden and the development of lung injury.
Thus, the most effective way to improve the disease outcomes and therefore reduce the worldwide health burden is the development of diagnostic tool for early detection.
