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This simultaneous radiopharmaceutical preparation lead to a significant reduction of radiation burden, reduction of amount of operator time (-50%), cost reduction (-46.2%) and, subsequently, to considerable gain in overall efficiency of the production process.
Unfortunately, low to moderate worm burden reduction of 0 33.4% was recorded after administration of a single oral dose of 200 mg/kg or 400 mg/kg to mice harboring S. japonicum.
An additional 38% of patients achieved tumor burden reduction of <30%.
Bacterial burden reduction of approximately five (lung) to ten (spleen and liver) fold was observed in various organs.
Notably, a retrospective analysis of RECORD-1 identified a best overall tumor burden reduction of 5% as the threshold for PFS benefit in everolimus-treated patients [ 16].
Mice in the vaccinated group by gene gun resulted in a significant liver egg burden reduction of 40.38% (P < 0.01) and 44.51% (P < 0.01) to the blank control group, in trail 1 and 2, respectively.
Similar(53)
Treatment of S. mansoni-infected mice with artemether at a total dose of 300 mg/kg resulted in total and female worm burden reductions of 66.7 and 90.1%, respectively, hence protecting the host from damage induced by schistosome eggs.
Note that the results of our financial forecasting and overall disease burden reduction are, of course, sensitive to the forecasted level of demand for rotavirus vaccine.
However, these subject areas did not necessarily enjoy a similar lead in scoring from a disease burden reduction point of view.
A complete LCA can highlight a possible shifting of burden where reduction of environmental impacts at one stage may come at the expense of another.
Arts Council England and national museums will share less of the burden with a reduction of 5% during 2015/16.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com