Despite the fact that infections substantially contribute to morbidity and mortality in patients with primary systemic vasculitis (PSV), data on risk factors and on the burden of specific infectious agents are scarce.
In this 'Adam's rib' scenario, an accessory RNA subunit RS evolves as a tool to enhance binding and positioning of aminoacyl-tRNA on the catalytic subunit, then acquires the "burden of specific recognition," and later on, one of its own parts assumes the role of a diffusible template.
Larger population-based studies are needed to determine the effects of mutations in CITED2 on the burden of specific types and constellations of malformations among humans, and to show whether these mutations have increased penetrance in the presence of high-fat maternal intake.
By contrast, the psychosocial burden of triage by repeat smear testing remained higher for longer and resulted in a greater total burden on the specific measure of distress for cervical screening.
Justice Anthony Kennedy, writing for the 6-to-3 majority, said the law violates First Amendment rights by imposing a "burden on protected expression" on specific speakers (drug marketers) and specific speech (information about the doctors and what they prescribed).
Ishigaki, K. et al. Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis.
Some reviews only include quantitative literature [ 9], some only focus on the needs and satisfaction of informal caregivers [ 10, 11] and others focus on specific burdens, such as PICS-F [ 7], post-traumatic stress disorder (PTSD) [ 12] or psychosocial burdens [ 13, 14].
The presence of edited sites may represent a "burden", since they are dependent on specific recognition sequences and trans-factors that need to be conserved to maintain editing activity.
In addition to the expected differences in full blood count, frequency of splenomegaly, JAK2 V617F allele burden, bone marrow cellularity, depending on specific MPN subtype, we found that the PV patients were significantly older than the other patients (P = 0.04), and ET patients were more often females (P = 0.04).
Previous approaches to measuring regulatory burdens based on counting words or measuring resources of federal regulatory agencies can make it difficult to identify the effect of regulations on specific industries.
