Over the past decades, a number of approaches have been developed, including evidence-based medicine, burden of disease analyses, cost-effectiveness analyses, and equity analyses.
Approximation methods are widely used to alleviate the computational burden of engineering analyses.
Approximation methods such as the response surface method (RS M are widely used to alleviate the computational burden of engineering analyses.
The choice made to use the average of all five plausible values was meant to ease the computational burden of the analyses.
These relative risks are used in the GBD study and have been used in a number of national level burden of disease analyses where no local data exist (19).
This might be a limitation of the study but on the other hand applying age-weights has also been criticised and evaluated as unacceptable on equity grounds [ 31], not empirically based [ 32] and adding complexity to burden of disease analyses that obscures the method and makes little overall difference to the rankings of diseases and injuries.
The first set contained only eukaryote sequences which passed tests of compositional homogeneity implemented in TREE-PUZZLE [ 89] while the second included available prokaryote sequences (several clusters of extremely closely related sequences from taxonomically similar bacteria were excluded to reduce the computational burden of phylogenetic analyses).
This simplification to one-dimension is necessitated from the computational burden of the analyses we perform, however, we note that this modelling choice represents the more complicated two and three-dimensional spaces where the attractant concentration only varies along one dimension.
The impact of perceived treatment choice on satisfaction with assigned treatment and on experienced chemotherapy burden was analysed by means of univariate analysis of variance.
One week following the completion of treatment, tumour burden was analysed in all animals by quantifying fluorescent tumour colonies as described in the Materials and Methods.
