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If hypothermic storage is a simple and broadly applicable method for enhancing cell stability, it also lead to logistic burden linked to the short shelf life of the product.
This double burden, linked to a rapid nutrition transition [ 12], had yet to be investigated in an urban West African environment.
Osteoarthritis (OA), a chronic degenerative disease of the joints, is a major health burden linked to high morbidity in the aging population [ 1, 2].
Genome-wide CNV burden linked to AP was analyzed with permutation tests in Plink in the 45 complete twin pairs and 4 unpaired twins.
Customs and traditions may define not only the sort of behaviours that warrant criticism [ 57], but also the burden linked to the relationship between patients and relatives as appraised by the latter, and every attempt should be made to pick up culturally sensitive issues [ 66, 67] of maladjusted interactions between patients and carers [ 68].
However, even if the inflammatory burden linked to diabetes not only may lead to the initiation and progression of atherosclerosis but also may contribute to plaque rupture and cardiovascular events, not much is known about inflammatory plaque differences as well as the plaque phenotype in subjects with versus those without diabetes.
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Embodied experiences of relief and flexibility made it possible, at least to some extent, to be released from individualistic expectations and pressures of success and perfection, as well as from gendered burdens linked to social and relational responsibility, self-criticism, and guilt.
This does, however, not imply that JAK2 allele burden is linked to development of fibrosis in individual cases, because allelic burden stayed stable during progression [ 12].
Increased oxidative stress burden, often linked to the chronic inflammation, is implicated in the tumorigenesis and leads to the elevated anti-oxidative response program in stress-adapted tumors.
Using an animal model of birth asphyxia based on 6-day-old rat pups, we have recently shown that the seizure burden is linked to an increase in brain extracellular pH that consists of the recovery from the asphyxia-induced acidosis, and of a subsequent plateau level well above normal extracellular pH.
These conditions are associated with a significant burden of pain linked to high morbidity and disability that is poorly assessed and undertreated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com