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Quantifying the asbestos-related lung cancer burden is difficult in the presence of this disease's multiple causes.
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Without established serologic correlates of protection against pneumococcal diseases, the actual impact of the 11-PncDT vaccine in reducing pneumococcal specific disease burden is difficult to estimate [ 19].
"I was just a 'dumb kid,' and carrying that burden is difficult," he recalled.
Tumor burden is difficult to estimate by endoscopy and conventional EUS.
Symptom burden is difficult to quantify objectively.
Biologic measurements of body burden are difficult to interpret in relation to the biologically effective dose and to early biologic response, but they can provide helpful links to associated health outcome.
Indirect knowledge transfer may have occurred by referring to existing burden estimates in research proposals, but the effect is difficult to assess.
Difficult students are difficult in detention too.
Antibiotic stewardship is perhaps the most important isolated measure that can be taken to prevent CDI related clinical burden, but it is difficult to accomplish in a growing population of elderly, dependent and institutionalized patients with consecutive healthcare associated infections.
Although the measurement of AA or anticholinergic burden in CNS is difficult, two methods have been devised.
The global burden of leptospirosis is difficult to quantify due to under-reporting and difficulties in establishing a serological diagnosis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com