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Intellectual disability is an extremely stigmatizing condition and involves utilization of large public health resources, but most data about its burden is based on studies conducted in developed countries.
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Interest rates, tax rates, and personnel burden are based on conservative assumptions.
Financial burden was based on the subjective views of the patients.
Estimates of vaccine impact on disease burden are based on the levels of transmission in each country, as described below.
Infant initial body burden was based on the assumption that intrauterine exposure to POPs is blood-flow limited.
Quantification of amyloid plaque burden was based on the image captured by immunohistochemical staining with antibody 6E10.
However, current estimates of disease burden are based on the same underlying assumptions irrespective of stroke type.
In these studies and many others from developed countries, the estimates of burden are based on hospitalisation rates.
This study on "total infection burden" was based on aggregated data, and both primary and revision arthroplasties were included in the analyses.
Another possible limitation is that estimates of future disease burden are based on assumptions about the number at risk of disease and about mortality within the population.
The qualitative health related behaviour questionnaire used to determine disease burden was based on the SF-12 short form questionnaire (SF-12® Health Survey© 1994).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com