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The burden indicator has shown itself to be less precise for specific toxicity effects but responsive to the whole spectrum of treatment sequelae (Bernhard et al, 2002).
We calculated a country's ranked burden score by adding together numerical values for each burden indicator, and organised countries based on this new variable.
First, we did a medical subject heading (MeSH) thesaurus search, combined with text word searches to obtain a full set of synonyms for the various combinations of three general concepts: [type of ARI disease] & [disease burden indicator] & [type of crisis].
The difference between their study and ours is that their sample included patients with prevalent as well as incident diabetes, used different comorbid illnesses to determine CCIGs, and used the relative risk score from the diagnostic cost groups (DxCG) as an illness burden indicator.
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Instead, we present summary data for each study in descriptive tables and provide ranges for the key burden indicators.
Drug availability and immunization coverage has improved while there has been limited decline in disease burden indicators [ 21].
Lastly, where the burden indicators were not reported but enough data (i.e. numerator, denominator at risk) were provided to compute them, we did so ourselves.
To calculate this composite ranked disease burden score we assigned numerical values to three burden indicators: the percentages of childhood deaths due to diarrhoea and malaria, and HIV prevalence among adults.
Global burden indicators not only give an idea of the scope of the disease under study, but can also be used to direct limited financial resources to sites where they can be most effective.
When other cancer burden indicators, like incidence and population-based survival are considered together with mortality, it is possible to discuss on the effectiveness of public health strategies and find clues on the respective role of different interventions.
Exposure biomarkers will receive most of the research emphasis in the near term, particularly body burden indicators of exposure to high-priority chemicals, such as benzene, ozone, selected heavy metals, and organophosphate pesticides.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com