Sentence examples for burden in the context from inspiring English sources

The current data narrow down the complex interactions of amino acid and lipid metabolism [37] to highlight the importance of a single marker, α HB, which may reflect oxidative burden in the context of IR.

This increased suppressive burden in the context of GVAX versus FVAX could be reducing the fraction of tumor-infiltrating effector T-cells which develop into optimal effectors as well as reducing the cooperative augmentation of effector function we observe with FVAX.

These estimates provide key information on future diabetes burden in the context of a multiethnic population.

If the STI burden in the context of PrEP use become too great, communities can and will make course corrections.

Little is known about how physicians perceive their patients' health-related financial burden in the context of primary care.

Future study into the relationship between possible biomarkers for Morquio A disease burden in the context of genotype phenotype relationship could provide improved early diagnosis and/or improved clinical management of Morquio A syndrome.

Given the many and complex linkages between climate processes and a health outcome, understanding the extent to which weather, climate variability, and climate change are affecting and may affect future health burdens in the context of other risk factors, and the temporal and spatial patterns of any changes, is challenging if not impossible without developing mathematical and statistical models.

Mathematical and statistical models are needed to understand the extent to which weather, climate variability, and climate change are affecting current and may affect future health burdens in the context of other risk factors and a range of possible development pathways, and the temporal and spatial patterns of any changes.

Here, we leverage large-scale exome-sequencing data to create an empirically based simulation framework to evaluate the impact of key parameters (background variation rates, locus heterogeneity, mode of inheritance, penetrance) on power in gene-based burden tests in the context of monogenic disorders.

The increasing CKD burden occurs in the context of lack of access of most of the world population to adequate healthcare and an incomplete understanding of the pathogenesis of CKD.

The increasing CKD burden occurs in the context of both a lack of access of most of the world population to adequate healthcare and an incomplete understanding of the pathogenesis of CKD that has prevented major advances in therapies to stop or reverse CKD progression in recent decades.