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In addition, MAPK3 was also observed to be under a hypermethylation burden in our study.
However, there were differences with lower seizure burden in our study (5.0 seizures/week vs. 9.5), history of generalized motor seizures (50vs.69%9%), and a slight male preponderance (56% in our study vs. 35%).
Thus, based on the range of adiponectin and the range of total plaque number, adiponectin levels account for approximately 3% of the variability in total plaque burden in our study population.
16 As found in different studies from the Eastern Mediterranean region, RVGE disease burden in our study was highest in children <2 years of age.
However, in order to reduce respondent burden in our study, we only asked about the presence of each of these impacts.
As mentioned above, the spousal symptoms of anxiety and depression and subjective well-being represent subjective caregiver burden in our study, and will thus be referred to as "subjective burden".
Similar(51)
Our MRI results were confirmed on the molecular level, as we found similar results, such as a 2.3-fold amplification in gene expression of CD44 the surrogate marker for tumor burden in our studies.
Using our data thus far, we found that symptom burdens in our study cohort at baseline were high despite treatment.
The burden found in our study is consistent with previous literature on the short-term implications of THI in SA (Al-Anazi 2004; Al-Habib et al. 2013; Chowdhury et al. 2014; WAHAB et al. 1989).
For this reason, it is likely that the actual societal impact of all ADR-related morbidity, both mild and serious, exceeds the burden described in our study.[7] Fourth, this study is based on the national situation in the Netherlands, with a full healthcare insurance coverage system and may be not representative for other countries.
The increased burden found in our study was not driven by large or de novo events, which have been described as causative in other neurodevelopmental disorders.
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