Sentence examples for burden in a model from inspiring English sources
Altogether, these results established our ability to precisely control total clot burden in a model that resembles the clinical pathology of venous thrombosis.
Both simplifications were adopted to reduce computational burden in a model where optimal adaptation is computed using a large number of model runs.
Treatment of mice with an anti-LOXL2 monoclonal antibody reduced the fibrotic burden in a model of cancer and lung fibrosis, in part via reduction in disease-associated fibroblasts.
The multiple logistic regression model revealed that the logarithm of GLP-1 was significantly associated with total coronary plaque burden in a model adjusted for age, sex, BMI, hypertension, diabetes, smoking, LDL, log.
Indeed, chronic (∼30 weeks) topical application of small quantities (40 nmol per animal) of TBE-31 twice a week resulted in dramatically reduced tumor multiplicity and burden in a model of ultraviolet radiation-mediated skin carcinogenesis in SKH-1 hairless mice receiving azathioprine treatment [19].
THZ significantly reduces bacterial burden in a mouse model of TB [19] and shows promising activity in a mouse model of MDR-TB.
More importantly, the hybrid 7 also showed very low cytotoxicity, and could significantly reduce the mycobacterial burden in a mouse model infected with autoluminescent H37Ra strain, which may serve as a lead compound for further development of new anti-tubercular agents.
Moreover, antibody-mediated FoxP3 protein therapy resulted in a clinically significant reduction in tumor burden in a syngeneic model of colon cancer metastasis to liver in Balb/c mice [7].
Systemic inhibition of HIF-1α by 2ME2 significantly decreased osteolytic lesion area and reduced tumor burden in a prevention model of MDA-MB-231 breast cancer bone metastasis, consistent with the previous studies using 4T1 cells [42].
Elastase inhibition by shRNA provides a means to decrease the tumor burden in a xenograft model.
Therefore, we hypothesized that suppression of elastase would significantly decrease tumor burden in a xenograft model.
