We sought to compare the cost-effectiveness of different interventions that have been shown to improve adherence with antihypertensive and lipid-lowering therapy, by combining a burden of nonadherence model framework with literature-based data on adherence-improving interventions.
This setting facilitates a great modeling flexibility but has an associated high computational burden, and a framework relying on kriging surrogate modeling is proposed here to address this challenge.
For the group of participants who perceived a higher burden level the framework of support available was necessary.
As determined by this study, more than a thousand genes contribute to the observed polygenic burden within the framework of this study.
In quantifying non-fatal, morbid health outcomes for a wide range of diseases and injuries, the burden of disease framework combines epidemiological parameters and severity weights for different health states [ 6].
This study used an incidence-based burden-of-illness framework to estimate the annual costs of bacterial conjunctivitis in the United States.
LONDON — Chancellor Angela Merkel of Germany stuck to her guns Wednesday, telling lawmakers on the eve of a crucial summit on the future of the euro that giving in to pressure to share debt burdens without a political framework in place would be "economically wrong and counterproductive".
This chapter is dedicated to alleviating the multiscale dilemma in terms of heavy computational burden of the multiscale design framework discussed in Chapter 1.
The main difficulty for doing so arrives from the computational complexity of the proposed framework and the burden of computational resources needed for its application, which would prevent the real-time prediction of fire spread scenarios.
