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Each microbiological burden evaluation included three different moments, as follows: (1) before patient admission, (2) six hours after admission, and (3) 24 hours after admission.
Given the need to minimize treatment burden, evaluation and treatment of sleep disturbance in this population may require clinical protocols specifically designed for patients with cancer.
In cancer patients, objective tumor burden evaluation is commonly accomplished by radiological methods.
For parasitic burden evaluation, two independent experiments were performed, on which 6-7 animals per group were used on Experiment 1, and 7-8 animals per group on Experiment 2. Following perfusion to recover the parasites, fragments of the intestine (terminal ileum) from each animal were separated and washed in saline solution.
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A surrogate model built with an improved semi-supervised learning method is employed to evaluate a part of individuals instead of the user to alleviate his/her burden in evaluation.
We focus on reducing the evaluation burden by presenting a semi-supervised learning assisted interactive genetic algorithm with large population.
The heavy evaluation burden of the user, however, is crucial and limits their applications in complex optimization problems.
They proposed two prototypes; in the first prototype, the fitness function is defined based on the ergonomic constraints to reduce the burden of user evaluation.
The empirical results demonstrate the strength of our algorithm in searching for satisfactory solutions and easing the evaluation burden of the user.
Although the use of subcutaneous xenograft models of ovarian cancer allowed for easy assessment of tumor burden and an evaluation of the extent of tumor targeting, this advantage also contributes to being a limitation of this study.
The evaluation burden of this phase is negligible if the channel can be supposed constant for several consecutive OFDM symbols, thus we focus on the second stage of the algorithm.
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