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In Ph− myeloproliferative neoplasms, the quantification of the JAK2V617F transcripts may provide some advantages over the DNA allele burden determination.
One kidney was used for fungal burden determination and the other was snap frozen in liquid nitrogen for subsequent RNA extraction and qRT-PCR analyses (Walker et al., 2009).
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The spatial aliasing is used to highly compress the full grid search into small angular sectors to reduce significant computational burden, and unique determination of DOA is finally obtained by implementing the ML algorithm with different sub-arrays selected from DSANA.
Following homogenation, aliquots were removed to measure chlamydial burden using IFU determination as described [20].
Carotid artery wall intima-media thickness (cIMT) is a widely accepted indicator of subclinical atherosclerotic burden, and its determination could be useful in identifying young adults at risk for premature coronary atherosclerosis (Slyper 2004).
The success of such therapeutic approach depends on (1) the expertise of the interventional radiologist to selectively catheterize the appropriate branch of artery, (2) the selection of patients with limited tumor burden, and (3) the determination of the maximal activity which can be safely injected to the patient.
Any new determination of burden of disease due to MSC should recognise that these disorders may be more prevalent in developing countries than previously estimated.
The interval between operations was based upon the physicians' intraoperative determination of disease burden and was not determined by a specific protocol.
Harriman, by contrast, was heir to a great railroad fortune, the product of Groton and Yale, whose only burden in life was a determination to equal his father's brilliant, if bare-knuckle, career.
As identified by the economic literature, using combinatorial auctions introduces a lot of complexity (winner determination and information burden) into the allocation process.
A more precise determination of the burden of lesions allows for better surgical planning (mastectomy versus conservative techniques) and is fundamental for the indication and planning of neoadjuvant chemotherapy [31].
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